If you're a resident of a state that has a medical school, your best bet is to apply there. State-run universities offer competitive advantages to residents and much lower tuition rates than non-residents are charged. For example, in 2008, The University of Nevada, Reno School of Medicine had 322 Nevada residents apply, and 52 of them were enrolled in the 2009 class. Of the 899 non-residents who applied, and only five were accepted. Those non-residents paid $38,885 in annual tuition, while the residents paid $13,520.
Grade point average (GPA) is an important statistic medical schools look for when accepting applicants. While many schools require an average GPA of 3.8 or 3.9, some schools more readily accept applicants with lower GPAs. For example, as of March 2011, Mercer University in Georgia had an incoming GPA average of 3.3 and the University of Illinois had an average incoming GPA of 3.4.
The MCAT is used by many schools to separate viable candidates from those who don't make the cut. You might have excellent grades, but a poor MCAT may leave you "out in the cold" with schools that have very high standards. If your MCAT score is below 3.5, consider Howard University in the District of Columbia and Morehouse School of Medicine in Georgia. These schools had freshman students entering with an average MCAT score of 3.4.
Academic requirements may not be your only consideration when looking into easier-to-get-into medical schools, since cost will usually have an impact the difficulty of attending. According to the American Academy of Medical Colleges, the first year of medical school at Temple University in 2010 was $78,888. On the other end of the spectrum, Texas A&M's resident tuition and fees for the same period were $15,362.