Hold the handle of the scalpel with the blade pointed away from your body. Rotate the scalpel until the entire removable blade is facing upward.
Grip the base of the scalpel blade with tweezers or forceps. Grip right above the slanted (non-blade) edge of the removable blade.
Lift upward with the tweezers or forceps. Listen for a small click, which indicates the blade unlocking.
Pull the removable blade from the tip, using the tweezers or forceps. Twist the blade gently if it does not come off easily.