Recognize that after college you'll be confronted with a tough job market. The more motivated you are to succeed, the better chance you'll have of acquiring good employment.
Consider where you want to live after college is over. If you don't want to move back in with your parents, work hard to save money and find a different place to live.
Realize this might be the last year you live in this town, your college town. Try out the restaurants you haven't eaten at, the museums you haven't seen and the places you haven't been to.
Start an exercise routine. Not only does exercise make you feel better physically, but also emotionally, which increases your motivation.
Meet with your college's career center employees to get advice on what you should do to prepare for life after college.
Team up with a friend to motivate each other. Give reminders to each other when one of you slacks off or opts to play video games instead of studying.