Place the shoe box on its side lengthwise, with the opening towards you.
Cut the radish in half, so that the inner rings are visible. This will be your nucleus. Make a dot near the center of the cut-side with the permanent marker to represent the nucleolus. This is a non- membrane bound structure composed of proteins and nucleic acids found within the nucleus.
With the needle and the fishing line, thread some fishing line through the radish and up through the top of the shoe box, using the thimble to brace your thumb as you push. Knot the fishing line on top of the box, letting the radish hang down about halfway into the box.
Rinse the sugar off of one half of two sour straws. Attach the smooth side of each sour straw to opposite sides of the radish nucleus. The smooth side represents the smooth ER (endoplasmic reticulum) and the sugared side represents the rough ER. Attach the unsupported end of each sour straw with some fishing line and secure them to the top of the box.
Tear several small pieces of tape from the roll. Sprinkle some large cake sprinkles onto the sticky side of each piece of tape. These sprinkles act as the Golgi vesicles. Use the needle to poke a hole through the tape. Thread some fishing line through the hole and attach them through the top of the box.
Tie some fishing line around several Cheetos in a chain and attach them next to the suspended sprinkles to act as the Golgi apparatus. Suspend carrot slices from the top of the box to act as mitochondria.
Suspend a mini marshmallow from the top of the box to act as the lysosome.
Cover the front of the box with plastic food wrap to simulate the cytoplasm. The box itself represents the cell membrane.
Make a list of the key of the food items and the cell elements they represent and secure it on top of the box to cover the fishing line knots.