Start the Dreamweaver CS4 program. Click the "HTML" option from the "New" column on the "Welcome" page that appears to create a new Dreamweaver web page. Click on the "Save" option in the "File" menu to save your Dreamweaver web page.
Click the "Image" option from the "Insert" menu on Dreamweaver's main menu bar. Select an image file to import into Dreamweaver from the file directory listing that is displayed.
Click on the image imported into the Dreamweaver document.
Click the "Properties" option to display the "Properties" panel so you can access Dreamweaver's hotspot tool.
Type a name for the hotspot you are going to create in the "Map" textbox in the "Properties" panel. Click the "Rectangle HotSpot Tool" directly below the "Map" textbox. Position your mouse cursor over the imported image and then click and drag your mouse to create a rectangular hotspot on the image. Release the mouse to finalize the hotspot's rectangular dimensions.
Press the "OK" button on the Dreamweaver dialog box that appears. Type in the URL in the "Link" text box in the "Properties" panel that you want to load into your web browser when the rectangle hotspot your created is clicked.
Press the "F12" key on your keyboard to preview your web page in your default browser. Position your mouse cursor over the location you drew your rectangle hotspot at. Click your left mouse button when the mouse cursor changes from a pointer to a hand cursor (indicating you are over the hotspot) to load the link you selected into your web browser.