* ἐμπορία (emporia): This is probably the closest single word and refers to trade, commerce, or a marketplace. It's a very common and versatile term.
* χρήμα (chrema): This word means "money" or "wealth," and so could be used in contexts relating to the financial aspect of commerce.
* πράσις (praxis): While not directly translating to "commerce," this word means "action" or "practice," and could be used in the context of commercial *activity*.
The most accurate translation will depend heavily on the context. For most purposes, ἐμπορία (emporia) is the safest and most appropriate choice.