* χρήσις (chrēsis): This is probably the closest single word and means "use," "usage," or "application." It implies a practical or functional use.
* επίδρασις (epidosis): This translates to "effect," "influence," or "impact." It would be suitable if the "use" resulted in a noticeable change or consequence.
* εφαρμογή (epharmogē): This means "application" or "implementation," and is appropriate if you're talking about applying something (a method, a law, etc.).
* απασχόληση (apascholēsi): This means "occupation," "employment," or "use (of time)." It's relevant if the "use" refers to something being occupied or employed for a purpose.
To choose the best word, you need to provide the context of how "use" is being employed in your sentence.