* The last degree in an academic program: This depends on the specific program. Some programs have a terminal degree (like a PhD), while others don't.
* The last degree of latitude or longitude: This would be 90° North or South latitude, and 180° East or West longitude, respectively.
* A metaphorical "last degree": This could refer to the final stage of something, the ultimate limit, or a point of no return.
Please provide more context for a more precise answer.