To answer your question properly, we need to clarify what drug you suspect might be used and then we can talk about which urine tests would detect it. For example, if you suspect someone used a stimulant, the test would look for amphetamines or other stimulant metabolites. If you suspect an opioid, the tests would search for specific opioids and their metabolites.
If you're concerned about drug use, please speak to a healthcare professional or a qualified drug testing facility. They can advise you on the appropriate testing procedures.