Why is the test for bacteriostasis and fungistasis carried out before sterility testing?

Before sterility testing, performing tests for bacteriostasis and fungistasis is crucial to rule out any inhibitors present in the final product that may interfere with the growth of microorganisms during sterility testing.

Bacteriostasis and fungistasis tests are conducted to detect the presence of substances in a product that inhibit or suppress the growth of bacteria and fungi, respectively. These inhibitory substances could potentially compromise the reliability of sterility testing by preventing the detection of viable microorganisms.

By carrying out bacteriostasis and fungistasis tests prior to sterility testing, it is possible to identify and eliminate potential inhibitors, ensuring that the sterility test results accurately reflect the presence or absence of viable microorganisms.