- Carlos, Prince of Asturias (1978–present): eldest child of Juan and the heir apparent to the Spanish throne. He is married to Letizia Ortiz Rocasolano and they have two daughters: Leonor, Princess of Asturias and Infanta Sofía.
- Infanta Elena, Duchess of Lugo (1963–present): second child of Juan and his first wife, María de las Mercedes of Bourbon-Two Sicilies. She is married to Jaime de Marichalar and they have two children: Felipe Juan Froilán and Victoria Federica de Marichalar Borbón.
- Infanta Cristina (1965–present): third child of Juan and his first wife, María de las Mercedes of Bourbon-Two Sicilies. She is married to Iñaki Urdangarin and they have four children: Juan Valentín, Pablo, Miguel, and Irene.
- Felipe VI, King of Spain (1968–present): fourth child of Juan and his first wife, María de las Mercedes of Bourbon-Two Sicilies. He is married to Letizia Ortiz Rocasolano and they have two daughters: Leonor, Princess of Asturias and Infanta Sofía.