* Τι κάνεις; (Ti kaneis?) - This is the most common and versatile way to say "How are you?" or "What are you doing?" It's informal and suitable for friends and family.
* Τι κάνετε; (Ti kanete?) - This is the polite form, used when addressing someone older, someone you don't know well, or multiple people. The ending changes to show the plural.
* Πώς περνάς; (Pos pernas?) - This translates more literally to "How are you passing (your time)?" It's informal and implies a more personal inquiry about well-being.
* Πώς τα πας; (Pos ta pas?) - Similar to the above, but even more informal. It literally translates to "How are you going (with things)?"
Therefore, Τι κάνεις; or Τι κάνετε; are generally safe and appropriate choices in most situations. The others offer slightly different nuances.