* αντίο (antio): This is probably the closest single-word equivalent and is widely used in most situations. It's a versatile farewell.
* γεια (ya): More informal, like "bye" or "hi" in English. It can be used as both a greeting and a farewell.
* Longer phrases, such as καλό ταξίδι (kaló taxídi) ("have a good journey") or καλήνύχτα (kaliníxta) ("good night") would be used in specific circumstances.
So, while αντίο (antio) is a good general answer, the most appropriate word depends on the situation and your relationship with the person you're saying goodbye to.