- Isaac Hayes: Singer, songwriter, and composer, known for his work in soul music such as the theme song for "Shaft".
- Penny Hardaway: Former professional basketball player who played for various NBA teams including the Orlando Magic and Memphis Grizzlies.
- Lisa Marie Presley: Daughter of Elvis Presley and a singer-songwriter in her own right.
- Justin Timberlake: Singer, songwriter, actor, and record producer who gained fame as a member of the boy band NSYNC before embarking on a successful solo career.
- Quavo: Rapper and member of the hip hop group Migos.
- Anfernee "Penny" Hardaway: Former NBA All-Star and current head coach of the Memphis Tigers men's basketball team.
- Elliott Perry: Former NBA player and current men's assistant basketball coach at the University of South Florida.
These are just a few examples of famous people who have attended the University of Memphis.