One idea for a creative medical terminology paper would be to analyze the origins of medical terms. Most medical terms originate from Greek or Latin root words. Your paper could break popular terms down into their most basic parts to discuss how the pieces come together to create meaning. If you have a background in Greek or Latin, this option might be for you; if you don't have such a background, you'll need to research the terms and analyze their meanings and evolution.
For example, take a medical term such as "infarction." An infarction is an area of tissue that has been oxygen-starved to death inside a body. This word comes from the Latin roots "in" and "farcire." "Farcire," meaning "to stuff," is related to the word "farce" and possibly "frequens," which means "crowded." One part of your paper could analyze how these original concepts may have been applied to such medical phenomena as cardiac infarctions.
One creative thesis for your medical terminology research paper would be to study how the terms are used (and abused) in contemporary society. Most people's knowledge of medical terminology doesn't extend beyond a rudimentary list of terms learned in health classes or through personal experience with illness. Your paper could focus on what terms are most commonly known and why this might be the case. You could even argue that with the popularity of medical dramas on television, more people are using medical terminology otherwise reserved for healthcare professionals. Another project idea would be to analyze why medical words are misused in contemporary society. For example, the words "infection" and "inflammation" refer to different afflictions (infection refers only to bacteria, while inflammation involves any bodily irritation), but they're often used interchangeably.
Another focus for your medical terminology research paper would be to analyze the grammar involved with using and writing these terms. For instance, the hyphen is often used to separate the prefixes and suffixes that make up medical terms. According to Medword.com, medical dictionary publishers are increasingly choosing to forgo this antiquated use of the hyphen and instead combine the terms; your paper could focus on why this might be the case. Your paper could also analyze the use of written elements such as italics, capitalization and underlining when writing medical terminology.