Ensure that the body surface area measurement is in meters squared. Ensure that the hemoglobin level is in grams per liter.
Multiply the body surface area by 135. In other words, calculate "BSA * 135."
Multiply the hemoglobin level by 13 and the difference between the venous oxygen saturation level and the arterial oxygen saturation level. In other words, calculate "13 * hemoglobin * (SaO2 - SvO2)."
Divide the result of Step 2 by the result of Step 3. The whole equation should be "(BSA * 135) / (13 * hemoglobin * (SaO2 - SvO2))." The result of this equation is the Fick number. The units of the number are in liters per minute.