* The Secret History (1992) - A dark and atmospheric novel about a group of Classics students at a prestigious New England college who become involved in a dangerous and destructive secret.
* The Little Friend (2002) - A Southern Gothic novel about a young girl's obsessive quest to find her brother's killer.
* The Goldfinch (2013) - A sprawling and ambitious novel about a young boy who survives a bombing in an art museum and becomes obsessed with a stolen painting.
She has also written a short story collection, The Handmaid's Tale (1985), which is not to be confused with Margaret Atwood's novel of the same name.