Here are some options depending on your perspective:
Based on longevity and influence:
* Lynda Barry: Her strip "Ernie Pook's Comeek" was groundbreaking and influential, blending humor and introspection. She's also a celebrated author, filmmaker, and teacher.
* Alison Bechdel: Her graphic memoir "Fun Home" broke barriers and won critical acclaim, making her a leading voice in graphic storytelling.
* Lynn Johnston: Creator of "For Better or For Worse," she tackled relatable family issues with both humor and depth.
* Trina Robbins: A pioneer in feminist comics, she was a key figure in the underground comics scene and has contributed significantly to comics history.
Based on popularity and mainstream success:
* Cathy Guisewite: "Cathy" was one of the most popular comic strips of the 80s and 90s, with a relatable, single woman protagonist.
* Berke Breathed: "Bloom County" and "Outland" were hugely popular strips known for their humor and social commentary.
* Hilary Price: "Rhymes with Orange" is a popular daily strip known for its quirky humor and relatable situations.
Based on specific genres:
* Phoebe Gloeckner: A master of graphic memoirs, her work explores complex issues with honesty and vulnerability.
* Raina Telgemeier: Known for her graphic novels aimed at young readers, she tackles challenging topics like family relationships, mental health, and identity.
* Mariko Tamaki: A critically acclaimed graphic novelist, she often tackles themes of gender, family, and queer identity.
Ultimately, the "comic strip queen" is a matter of perspective. Each of these women has made significant contributions to the world of comics, and their work deserves recognition and appreciation.