- Superman: Superman is one of the most powerful superheroes in the DC Comics universe, and he has defeated Doomsday on several occasions. Superman's strength, speed, and invulnerability make him a formidable opponent for Doomsday.
- The Flash: The Flash is another incredibly powerful superhero in the DC Comics universe. His super speed allows him to move faster than Doomsday can react, and he has used this speed to defeat Doomsday in the past.
- Wonder Woman: Wonder Woman is an incredibly skilled warrior, and she has also defeated Doomsday in the past. Wonder Woman's strength, speed, and combat skills make her a dangerous opponent for Doomsday.
- Martian Manhunter: Martian Manhunter is a powerful alien superhero, and he has defeated Doomsday in the past. Martian Manhunter's abilities include telepathy, telekinesis, and shape-shifting, which make him a versatile opponent for Doomsday.
- Batman: Batman is not as physically powerful as the other characters on this list, but he has defeated Doomsday by using his intelligence and planning. Batman's knowledge of Doomsday's weaknesses and his ability to exploit them have allowed him to defeat Doomsday in the past.