Methods of Serology

Serology is the study of blood serum either to determine a person’s illness or forensically to gather evidence.
  1. How Serology Works

    • Blood is drawn from a person either from his inner arm near the elbow or from the top of the hand. The blood is then sent to a laboratory where the serum is separated from the red blood cells. The serum can then be tested in a variety of ways to determine and detect infection. Once the infection is detected, the appropriate antibiotic can be prescribed.

    Types of Serum Tests

    • Many different types of tests can be performed on blood serum based on the suspected illness or disease. A few of the more common tests include agglutination, which determines the clumping or massing of cells and how they react to antigens; complement fixation, which shows the presence of an antibody and allows the antibody to bind to the antigen to see how it reacts; and fluorescent antibodies, which shows the distribution of specific protein signatures left by antibodies under different lighting. Each antibody reacts to differently to different fluorescent frequencies.

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