* The college: Different universities and colleges have different admissions standards. A highly selective university might expect a higher grade than a less selective one.
* The intended major: Students applying for majors in science, engineering, medicine, or related fields will almost certainly need a strong chemistry background, often including specific courses like AP Chemistry or a high school chemistry course with a good grade. Other majors may not require any high school chemistry at all.
* The specific program: Even within a university, different programs might have varying chemistry prerequisites. For example, a pre-med program might require a higher grade in chemistry than a general biology program.
In short, you need to check the admissions requirements of the specific colleges and programs you're interested in. Their websites will usually list the required courses and any minimum grade expectations. Contacting the admissions office directly can also provide definitive answers.