- Oscars:
- Best Actor for "The Philadelphia Story" (1940)
- Golden Globes:
- Best Actor in a Motion Picture - Drama for "The Greatest Story Ever Told" (1965)
- Best Actor in a Motion Picture - Musical or Comedy for "The Man Who Knew Too Much" (1956)
- Cecil B. DeMille Award (1968)
- BAFTAs:
- Best Actor for "The Man Who Knew Too Much" (1956)
- Emmy Awards:
- Outstanding Actor in a Single Performance or a Series (1959)
- Grammy Awards:
- Best Spoken Word Album for "James Stewart: The American Dreamer" (1969)
- Tony Awards:
- Special Award for "Harvey" (1947)
- Honorary Doctorates:
- Doctor of Laws from Princeton University (1950)
- Doctor of Fine Arts from the University of California, Los Angeles (1970)
- Doctor of Humane Letters from Dartmouth College (1975)
- Other Awards:
- Presidential Medal of Freedom (1985)
- National Medal of Arts (1988)
- AFI Life Achievement Award (1990)
- National Cowboy & Western Heritage Museum Western Heritage Award (1992)
- Screen Actors Guild Life Achievement Award (1995)
- Kennedy Center Honors (1999)