- NASA Space Flight Medals (2)
- Aviation Week and Space Technology Laurel (1983)
- National Space Club Gus Grissom Award (1983)
- The Lovelace Woman of the Year Award (1983)
- Harvard Alumni Association Medal (1984)
- California Museum of Science and Industry Space Medal (1984)
- Lindbergh Award for Space Exploration (1984)
- General Motors Cancer Research Foundation's Kettering Award (1985)
- Golden Plate Award of the American Academy of Achievement (1985)
- National Women's Hall of Fame (1993)
- Women in Technology International Hall of Fame (1993)
- National Medal of Science (2003)
- U.S. Astronaut Hall of Fame (2003)
- American Institute of Aeronautics and Astronautics (AIAA) Von Karman Award (2006)
- Philadelphia Award (2012)