Eisner Awards:
- 2007: Best Publication Design (for Amulet Book One: The Stonekeeper)
- 2009: Best Children's Graphic Novel (for Amulet Book Three: The Cloud Searchers)
- 2010: Best Children's Graphic Novel (for Amulet Book Four: The Last Council)
- 2011: Best Publication Design (for Amulet Book Five: The Fires of the Shadow Realm)
- 2012: Best Publication Design (for Amulet Book Six: The Prince of the Elves)
- 2013: Best Publication Design (for Amulet Book Seven: The Stonekeeper's Curse)
Harvey Awards:
- 2008: Best Children's or Young Adult Book (for Amulet Book Two: The Stonekeeper's Curse)
- 2009: Best Children's or Young Adult Book (for Amulet Book Three: The Cloud Searchers)
- 2010: Best Children's or Young Adult Book (for Amulet Book Four: The Last Council)
- 2011: Best Children's or Young Adult Book (for Amulet Book Five: The Fires of the Shadow Realm)
- 2012: Best Children's or Young Adult Book (for Amulet Book Six: The Prince of the Elves)
- 2013: Best Children's or Young Adult Book (for Amulet Book Seven: The Stonekeeper's Curse)
YALSA Awards:
- 2009: Michael L. Printz Award Honor Book (for Amulet Book Three: The Cloud Searchers)
- 2010: Michael L. Printz Award Honor Book (for Amulet Book Four: The Last Council)
- 2011: Michael L. Printz Award Honor Book (for Amulet Book Five: The Fires of the Shadow Realm)
- 2012: Michael L. Printz Award Honor Book (for Amulet Book Six: The Prince of the Elves)
- 2013: Michael L. Printz Award Honor Book (for Amulet Book Seven: The Stonekeeper's Curse)
Other Awards:
- 2008: National Cartoonists Society Reuben Award for Outstanding Cartoonist of the Year
- 2009: New York Times Bestseller (for Amulet Book Three: The Cloud Searchers)
- 2010: New York Times Bestseller (for Amulet Book Four: The Last Council)
- 2011: New York Times Bestseller (for Amulet Book Five: The Fires of the Shadow Realm)
- 2012: New York Times Bestseller (for Amulet Book Six: The Prince of the Elves)
- 2013: New York Times Bestseller (for Amulet Book Seven: The Stonekeeper's Curse)