Here's how the process generally works:
1. Writing the Book: You write your entire manuscript, edit and polish it thoroughly.
2. Finding an Agent: You query literary agents, sending them your manuscript or a sample chapter with a query letter.
3. Agent Representation: If an agent is interested, they will sign you as a client, becoming your representative.
4. Agent Submission: The agent will then submit your manuscript to publishers, including HarperCollins, if they believe it's a good fit.
5. Publisher Review: HarperCollins editors will review your manuscript and decide whether to offer you a publishing contract.
In summary: You need to have your full manuscript completed and find a literary agent who will represent you and submit your work to publishers like HarperCollins.