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What is the difference between HSV 1 and 2?

The main difference between HSV-1 and HSV-2 lies primarily in their typical site of infection:

* HSV-1 (Herpes simplex virus type 1): Most commonly associated with oral herpes, causing cold sores or fever blisters around the mouth. However, it can also infect the genitals.

* HSV-2 (Herpes simplex virus type 2): Most commonly associated with genital herpes. While it can occasionally cause oral herpes, this is less frequent.

While their typical locations differ, it's crucial to understand that both viruses can infect both the mouth and genitals. This means that you can get oral herpes from HSV-2 and genital herpes from HSV-1. The distinction is more about the *usual* location of infection, not an absolute limitation.

Beyond their typical location, there are some subtle differences in the severity and frequency of outbreaks, with HSV-2 infections often leading to more frequent and severe genital outbreaks than HSV-1 infections. However, this is not always the case, and individual experiences can vary greatly. The severity of an infection depends on many factors including the individual's immune system.

Finally, both HSV-1 and HSV-2 are lifelong infections. Once infected, the virus remains in the body, even if symptoms are not present. This latent nature of both viruses means they can reactivate periodically, causing outbreaks.

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