University entry requirements vary greatly depending on the university, the course, and the specific year. While a grade C/4 in GCSE Maths used to be a common requirement, many universities now accept a grade D/3 or even a lower grade, or may offer alternative pathways like foundation courses.
You absolutely need to check the entry requirements directly on the university and course websites you are interested in. Don't rely on generalisations. The information provided there will be the definitive answer.