When used at the end of a letter, "best" typically means "with best wishes" or "with all my best." It can also be used to express a sense of admiration or respect, or to convey a sense of warmth and friendliness.
For example, in a personal letter to a friend or family member, you might write, "Take care and all my best." In a business letter, you might write, "I look forward to hearing from you. Best regards."
"Best" is a versatile closing salutation that can be used in many different situations. It is a simple but effective way to show your appreciation for the recipient and your interest in maintaining a positive relationship with them.