Accept the things you can't change. Maybe you think it's the absolute worst time for X to happen, and it seems like when it rains bad luck, it pours. If you feel a victim of unbelievably bad timing, try to accept the circumstances instead, and consider them as a wake-up call to clean up certain areas of your life in order to enjoy future prosperity.
Believe in destiny. If you believe all events in your life are working towards a greater good or your own spiritual and personal development, then that trust will help you to capitalize on whichever challenges you face. The better and sooner you deal with your immediate challenges, the more prepared you'll be to embrace the opportunities that follow them.
Look back on times in your life when the timing was perfect. Maybe you got laid off from a job, only to get an even better position that you never would have looked for otherwise. Perhaps you met your soul mate soon after getting out of a bad relationship. If you can find patterns of perfect timing in your past, it will help you to recognize and have faith in them in the future.
Become pro-active about challenges in your life. If one area of your life is not going well, chances are that at least another area is. For example, if you find yourself suddenly single, then consider it a chance to focus on other areas of your life, such as work or friends.