* Neil Armstrong: The first man to walk on the moon. While he didn't graduate (he left to join the Navy), his time at Purdue was significant.
* Dave Bautista: Professional wrestler and actor (Guardians of the Galaxy, Blade Runner 2049).
* Venus and Serena Williams: Tennis superstars (though information about their degree completion varies).
* Jenna Fischer: Actress (The Office).
It's worth noting that the fame of alumni can be subjective and the list could be much longer depending on the criteria used (e.g., level of fame, field of achievement, degree completion).