* The History of German Literature: This is a significant area of his research, and he authored several books on this topic, such as "Die deutsche Literatur von den Anfängen bis zur Gegenwart" (German Literature from its Beginnings to the Present).
* Theories of Literature and Literary Criticism: He was a prominent figure in the study of literary theory, analyzing the work of major theorists like Nietzsche and analyzing the history of literary criticism.
* Individual Authors and Works: He wrote extensively on individual German authors, including Goethe, Schiller, Hölderlin, and Kleist, and delved deep into their works and literary significance.
* German Romanticism and the Enlightenment: He was particularly interested in the impact of these movements on German literature and culture.
Here are some of his most well-known publications:
* Die deutsche Literatur von den Anfängen bis zur Gegenwart (German Literature from its Beginnings to the Present)
* Goethe: Der Mensch, der Dichter, das Werk (Goethe: The Man, the Poet, the Work)
* Schiller: Der Mensch und das Werk (Schiller: The Man and the Work)
* Hölderlin: Sein Leben und sein Werk (Hölderlin: His Life and Work)
* Kleist: Sein Leben und sein Werk (Kleist: His Life and Work)
* Die deutsche Literatur vom Mittelalter bis zur Gegenwart (German Literature from the Middle Ages to the Present)
* Der deutsche Geist in der europäischen Literatur (The German Spirit in European Literature)
Von Wiese was a highly influential figure in German literary studies and his works continue to be read and studied today.