Here's why:
* The letter is crucial: The letter is a key piece of evidence that reveals the connection between Dr. Manette and the Marquis, who unjustly imprisoned him for 18 years.
* The search: The Defarges, particularly Madame Defarge, are determined to find this letter. They know its importance in their mission of revenge.
* The setting: The search takes place in the wine-shop, which serves as a hub for revolutionary activity and where Madame Defarge is a key figure.
Let me know if you'd like more information on any aspect of this chapter!