* The Amazing Spider-Man: A cultural icon, Spider-Man's popularity is undeniable. It's been translated into numerous languages, adapted for movies, TV shows, video games, and more.
* Superman: Another superhero who transcends borders, Superman is a symbol of hope and justice, known worldwide.
* Batman: The Dark Knight is a global phenomenon, celebrated for his intelligence, resourcefulness, and brooding persona.
* The Avengers: This superhero team, featuring iconic characters like Iron Man, Captain America, Thor, and Hulk, has garnered immense popularity worldwide due to its blockbuster movie franchise.
* The Walking Dead: This zombie horror comic series has a massive global following, fueled by its successful TV adaptation.
* Manga and Anime: While not a single comic book, manga and anime, particularly titles like Dragon Ball, One Piece, Naruto, and Attack on Titan, have a massive global fanbase.
Ultimately, popularity is subjective and depends on individual preferences. What's considered the "most popular" comic book will change depending on factors like age, cultural background, and interests.