Based on powers/abilities:
* The Man of Steel: Superman
* The Scarlet Speedster: The Flash
* The Webslinger: Spider-Man
* The Wallcrawler: Spider-Man
* The First Family: The Fantastic Four
* The Dark Knight: Batman
* The Emerald Archer: Green Arrow
* The Merc with a Mouth: Deadpool
* The Caped Crusader: Batman
* The Amazing Amazon: Wonder Woman
Based on personality/origin:
* The Boy Wonder: Robin
* The Silver Surfer: Silver Surfer
* The Kingpin: Kingpin
* The Green Goblin: Green Goblin
* The Joker: Joker
* The Punisher: Punisher
* The Thing: The Thing (Fantastic Four)
* The Human Torch: Human Torch (Fantastic Four)
* The Visionary: Professor X
Based on location/affiliation:
* The Queen of Atlantis: Aquaman
* The King of Wakanda: Black Panther
* The Protector of Gotham: Batman
* The Defender of New York: Daredevil
Unique and creative:
* The Blue Beetle: Blue Beetle
* The Crimson Bolt: Captain Marvel (1960s)
* The Silver Age Sentry: Sentry
* The Big Red Cheese: The Thing (Fantastic Four)
* The Wall: The Thing (Fantastic Four)
Funny and satirical:
* The Bat-Signal: Batman
* The Amazing Spider-Man (and his Amazing Friends): Spider-Man
* The X-Men (and their Uncanny Adventures): X-Men
* The Unbreakable Man: The Thing (Fantastic Four)
* The Friendly Neighborhood Spider-Man: Spider-Man
Remember: Nicknames often reflect the character's personality, powers, and role in the story.
Bonus: Don't forget that some characters are known by their real names, like Bruce Wayne, Clark Kent, or Peter Parker, and use their heroic aliases as their secret identities.
Have fun with it! The world of comic book nicknames is full of creative possibilities!