* First Mate William Murdoch: The first mate of the Titanic, who is on watch during the collision with the iceberg. He survives the sinking but is later remembered as a hero for his actions during the disaster.
* Captain Edward John Smith: The captain of the Titanic, who is highly regarded by his crew and passengers. He goes down with the ship after ordering the evacuation of the women and children.
* Thomas Andrews: The chief designer of the Titanic, who is on board during its maiden voyage. He is aware of the ship's flaws but is unable to persuade Captain Smith to reduce its speed.
* Molly Brown: An American socialite and philanthropist who is traveling on the Titanic with her husband. She becomes a leader among the other survivors and helps to organize the lifeboats.
* Margaret Brown: A British nurse who is traveling on the Titanic with her family. She is instrumental in helping to evacuate the women and children from the ship.
* John Jacob Astor IV: An American businessman and socialite who is one of the wealthiest men on board the Titanic. He goes down with the ship after choosing to stay with his wife, Madeleine.
* John B. Thayer: An American businessman and politician who is traveling on the Titanic with his wife and children. He survives the sinking but loses his son in the disaster.